Sialic acids: Key determinants for invasion by the Apicomplexa
نویسندگان
چکیده
منابع مشابه
Sialic acids: key determinants for invasion by the Apicomplexa.
Sialic acids are ubiquitously found on the surface of all vertebrate cells at the extremities of glycan chains and widely exploited by viruses and bacteria to enter host cells. Carbohydrate-bearing receptors are equally important for host cell invasion by the obligate intracellular protozoan parasites of the phylum Apicomplexa. Host cell entry is an active process relying crucially on proteins ...
متن کاملTerminology for sialic acids.
We write on behalf of the Nomenclature Committee of the International Union of Biochemistry to comment on the proposal by Scott et al. (1982) to change the name of neuraminic acid to amino-sialosonic acid as a consequence of allotting the name sialose to a hypothetical 3-deoxynonulose. They further propose symbolizing sialose as Sia, sialosonic acid as SiaA, and aminosialosonic acid as SiaNA. W...
متن کاملBiosynthesis of sialic acids by Neisseria meningitidis.
Recent reports from this laboratory (2-4) and other laboratories (5, 6) have elucidated the pathway of biosynthesis of N-acetylneuraminic acid from N-acetyl-n-mannosamine and phosphoenolpyruvic acid in mammalian systems. The over-all biosynthetic reaction for rat liver and bovine submaxillary gland is catalyzed by 3 enzymes: a kinase, a condensing enzyme, and a dephosphorylating enzyme. N-Acety...
متن کاملThe biosynthesis of sialic acids.
The sialic acids (1) have in common a 9 carbon carboxylic acid, neuraminic acid (Fig. l), which may be regarded as a condensation product of a 3 carbon and a 6 carbon unit. Neuraminic acid itself is not found naturally, but several Nand O-substituted derivatives are widely distributed in nature (1). Chemical (2-4) and enzymic (5-7) degradations of N-acetylneuraminic acid have shown that this su...
متن کاملDiversity in the sialic acids.
It is now more than 50 years since N-acetyl-neuraminic acid was first discovered and subsequently characterized by several groups (reviewed in Roseman, 1970; Gottschalk, 1972; Rosenberg and Schengrund, 1976; Schauer, 1982; Faillard, 1989). Relatively soon after its discovery, it became apparent that this molecule was actually the major member of a family of compounds related to neuraminic acid ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal for Parasitology
سال: 2010
ISSN: 0020-7519
DOI: 10.1016/j.ijpara.2010.04.007